Juvenile Myasthenia Gravis: Musk Positive: with 3 Cardinal signs
International Journal of Development Research
Juvenile Myasthenia Gravis: Musk Positive: with 3 Cardinal signs
Received 19th December, 2024; Received in revised form 27th December, 2024; Accepted 14th January, 2025; Published online 27th February, 2025
Copyright©2025, Agrata Sharma et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Anti muscle specific tyrosine kinase (Musk) antibody is the most common antibody identified in seronegative myasthenia gravis (SNMG). Juvenile onset musk myasthenia has different clinical course as demonstrated in our case with spontaneous remission followed by resurgence of symptoms with ocular complaints. Musk myasthenia characteristically presents with bulbar and respiratory muscle involvement with a high rate of myasthenic crisis. Early identification is necessary to decrease the incidence of myasthenic crisis. We report a atypical case of musk myasthenia gravis with 3 cardinal signs which responded completely to immunosuppressants.
