Isolation and structural elucidation of secondary metabolites from allophylus semidentatus of the extracts and their antimicrobial, antioxidant and cytotoxic activity
International Journal of Development Research
Isolation and structural elucidation of secondary metabolites from allophylus semidentatus of the extracts and their antimicrobial, antioxidant and cytotoxic activity
Received 09th July, 2022; Received in revised form 27th July, 2022; Accepted 24th August, 2022; Published online 20th September, 2022
Copyright © 2022, Yohans José Martínez Moncada et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Some Sapindaceae plants are used in folk medicine, food and also in the pharmaceutical field. Allophylus semidentatus (Sapindaceae) is a wild plant that is being studied for the first time. In this investigation, the metabolites were extracted by using polar solvent as methanol, hexane, chloroform and ethyl acetate. Chromatographic and spectroscopic techniques were used for the isolation and identification of compounds. Extracts from the branches revealed the presence of steroids/triterpenes, flavonoids, alkaloids and coumarins. Metabolites were isolated by chromatography. The results of 1HNMR and 13CNMR showed the presence of four compounds allantoin, friedelin, campesterol and β-sitosterol. These compounds have been isolated from this plant for the first time. The anticancer, biological and antimicrobial activity of the extracts were also studied. This study highlights the bioactive potential of Allophylus semidentatus fractions which can lead to the development of drugs intended for the treatment of cancer.
